Complimentary shipping over $200•Xpresspost delivery in 1–2 business days•Order by 5 PM ET for same-day dispatch•Independently re-verified COAs — 99%+ purity• Complimentary shipping over $200•Xpresspost delivery in 1–2 business days•Order by 5 PM ET for same-day dispatch•Independently re-verified COAs — 99%+ purity•
Metabolic Signalling

AICAR · 50 MG

★★★★★4.9 · independently verified
$65.00
● In stock · ships same business day
AMPK-activating AMP analog studied as a metabolic exercise mimetic.
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Standard (1 vial) $65.00
10-Pack (Per Vial) $52.00
10-Pack Total $520.00
  • Includes an independently verified COA
  • Xpresspost in 1–2 business days · free past 0
  • Keep at 2–8 °C · reconstitute with bacteriostatic water

DESCRIPTION

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is an endogenous nucleoside intermediate that acts as a direct agonist of AMP-activated protein kinase (AMPK), the primary sensor of cellular energy status.

BENEFITS (RESEARCH FOCUS)

  • AMPK Activation: Directly stimulates AMPK signaling without altering resting cellular ATP to ADP ratios.
  • Mitochondrial Biogenesis: Researched for upregulating PGC-1alpha expression and promoting mitochondrial organelle density.
  • Insulin-Independent Glucose Transport: Investigated for facilitating GLUT4 receptor translocation to cell membranes.

WHAT RESEARCHERS LOOK AT

  • Phosphorylation of AMPK at Thr172 and downstream acetyl-CoA carboxylase (ACC)
  • Mitochondrial respiration rates and oxidative enzyme expression
  • Non-insulin-dependent glucose uptake assays in skeletal muscle cells

QUICK SPECS

  • Form: Lyophilized crystalline powder
  • Purity: >99% (RP-HPLC)
  • Packaging: 1 laboratory vial
  • Grade: Analytical research standard
  • Reconstitution: Dissolve in sterile aqueous laboratory buffer
  • Storage: Keep sealed at 2-8 deg C, desiccated

Quality Assurance

Each batch is independently verified for purity, identity, and sterility by Peptide Test Canada. A Certificate of Analysis is available for every lot. All compounds are produced under strict quality control conditions and shipped under cold-chain protocols from within Canada.

For laboratory research use only. Not for human or veterinary administration. This product is not represented as authorized by Health Canada or the U.S. FDA for diagnostic, therapeutic, preventive, or other clinical use. Research-use labeling does not create an exemption from applicable regulatory requirements. Researchers and purchasers are responsible for compliance with all applicable laws and regulations.
Read our full Regulatory & Research Use Disclaimer.

Matched batch certificate

Each batch arrives with its own Certificate of Analysis, and the batch number on your vial links straight to the published certificate. Look up any batch on our Testing & COAs page.

Shipping

Place an order before 5 PM ET and it ships the same business day by Xpresspost, arriving at most Canadian addresses within 1–2 business days. Orders over 0 ship free automatically.

Storage & handling

Keep refrigerated at 2–8 °C and shielded from light. Intended for laboratory research only — not for human consumption.

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