Complimentary shipping over $200•Xpresspost delivery in 1–2 business days•Order by 5 PM ET for same-day dispatch•Independently re-verified COAs — 99%+ purity• Complimentary shipping over $200•Xpresspost delivery in 1–2 business days•Order by 5 PM ET for same-day dispatch•Independently re-verified COAs — 99%+ purity•
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Lab Tested · 99%+ 5-Amino-1MQ
Metabolic Signalling

5-Amino-1MQ

★★★★★4.9 · independently verified
Price range: $40.00 through $125.00
● In stock · ships same business day
NNMT inhibitor studied for NAD+ salvage and adipocyte metabolism.
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Weight
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Standard (1 vial) $40.00
10-Pack (Per Vial) $32.00
10-Pack Total $320.00
  • Includes an independently verified COA
  • Xpresspost in 1–2 business days · free past 0
  • Keep at 2–8 °C · reconstitute with bacteriostatic water

DESCRIPTION

5-Amino-1MQ is a targeted membrane-permeable small molecule developed to selectively inhibit nicotinamide N-methyltransferase (NNMT). By blocking NNMT activity in cytosolic pathways, the compound prevents the methylation of nicotinamide, preserving cellular S-adenosylmethionine (SAM) levels and elevating intracellular NAD+ pools in experimental metabolic models.

BENEFITS (RESEARCH FOCUS)

  • NNMT Enzymatic Blockade: Evaluated for reducing 1-methylnicotinamide (1-MNA) formation and maintaining cellular methyl donor balance.
  • Cellular Energy Regulation: Investigated in metabolic assays for modulating basal metabolic flux and NAD+/NADH ratios.
  • Adipocyte Signaling: Researched in diet-induced obesity models for its effects on lipid homeostasis and fat cell differentiation.

WHAT RESEARCHERS LOOK AT

  • Intracellular NAD+ and SAM concentration dynamics
  • 1-MNA metabolite generation rate in adipocyte cell cultures
  • Expression of lipogenic and oxidative metabolic gene markers

QUICK SPECS

  • Form: Lyophilized solid (fine white powder)
  • Purity: >99% (High-Performance Liquid Chromatography)
  • Packaging: 1 sealed glass vial
  • Grade: High-purity laboratory research compound
  • Reconstitution: Dilute with sterile laboratory solvent or bacteriostatic water
  • Storage: Store refrigerated at 2-8 deg C, protected from light and humidity

Quality Assurance

Each batch is independently verified for purity, identity, and sterility by Peptide Test Canada. A Certificate of Analysis is available for every lot. All compounds are produced under strict quality control conditions and shipped under cold-chain protocols from within Canada.

For laboratory research use only. Not for human or veterinary administration. This product is not represented as authorized by Health Canada or the U.S. FDA for diagnostic, therapeutic, preventive, or other clinical use. Research-use labeling does not create an exemption from applicable regulatory requirements. Researchers and purchasers are responsible for compliance with all applicable laws and regulations.
Read our full Regulatory & Research Use Disclaimer.

Matched batch certificate

Each batch arrives with its own Certificate of Analysis, and the batch number on your vial links straight to the published certificate. Look up any batch on our Testing & COAs page.

Shipping

Place an order before 5 PM ET and it ships the same business day by Xpresspost, arriving at most Canadian addresses within 1–2 business days. Orders over 0 ship free automatically.

Storage & handling

Keep refrigerated at 2–8 °C and shielded from light. Intended for laboratory research only — not for human consumption.

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