Complimentary shipping over $200Xpresspost delivery in 1–2 business daysOrder by 5 PM ET for same-day dispatchIndependently re-verified COAs — 99%+ purity Complimentary shipping over $200Xpresspost delivery in 1–2 business daysOrder by 5 PM ET for same-day dispatchIndependently re-verified COAs — 99%+ purity
Metabolic Signalling

AICAR · 50 MG

★★★★★4.9 · independently verified
$65.00
● In stock · ships same business day
AMPK-activating AMP analog studied as a metabolic exercise mimetic.
  • Includes an independently verified COA
  • Xpresspost in 1–2 business days · free past 0
  • Keep at 2–8 °C · reconstitute with bacteriostatic water

DESCRIPTION

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is an endogenous nucleoside intermediate that acts as a direct agonist of AMP-activated protein kinase (AMPK), the primary sensor of cellular energy status.

BENEFITS (RESEARCH FOCUS)

  • AMPK Activation: Directly stimulates AMPK signaling without altering resting cellular ATP to ADP ratios.
  • Mitochondrial Biogenesis: Researched for upregulating PGC-1alpha expression and promoting mitochondrial organelle density.
  • Insulin-Independent Glucose Transport: Investigated for facilitating GLUT4 receptor translocation to cell membranes.

WHAT RESEARCHERS LOOK AT

  • Phosphorylation of AMPK at Thr172 and downstream acetyl-CoA carboxylase (ACC)
  • Mitochondrial respiration rates and oxidative enzyme expression
  • Non-insulin-dependent glucose uptake assays in skeletal muscle cells

QUICK SPECS

  • Form: Lyophilized crystalline powder
  • Purity: >99% (RP-HPLC)
  • Packaging: 1 laboratory vial
  • Grade: Analytical research standard
  • Reconstitution: Dissolve in sterile aqueous laboratory buffer
  • Storage: Keep sealed at 2-8 deg C, desiccated

Quality Assurance

Each batch is independently verified for purity, identity, and sterility by Peptide Test Canada. A Certificate of Analysis is available for every lot. All compounds are produced under strict quality control conditions and shipped under cold-chain protocols from within Canada.

This compound is available exclusively for in vitro laboratory research and scientific study conducted within Canada. It is not a drug, natural health product, or food product as defined under the Food and Drugs Act (R.S.C., 1985, c. F-27). It is not approved for human consumption, veterinary use, or any diagnostic or therapeutic application. This product has not been evaluated by Health Canada. Researchers are responsible for compliance with all applicable federal, provincial, and local regulations.

Matched batch certificate

Each batch arrives with its own Certificate of Analysis, and the batch number on your vial links straight to the published certificate. Look up any batch on our Testing & COAs page.

Shipping

Place an order before 5 PM ET and it ships the same business day by Xpresspost, arriving at most Canadian addresses within 1–2 business days. Orders over 0 ship free automatically.

Storage & handling

Keep refrigerated at 2–8 °C and shielded from light. Intended for laboratory research only — not for human consumption.

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