Semax Nasal Spray 10mg · 10 ML

Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from adrenocorticotropic hormone (ACTH 4–10).
It is studied for its effects on attention, memory, stress resilience, and post-stroke recovery, with research interest in neurotrophin pathways.

Product Highlights

• Each vial contains 10 mL solution (~100 sprays)
• Each spray delivers 0.1 mL = 100 mcg Semax
• Total Semax Content: 10 mg per vial
• Specialized pharmaceutical-grade nasal solution — designed for comfort and ease on the nose
• Unlike many other nasal sprays, this formula avoids irritation and dryness
• Packaged in Class A, lead-free pharmaceutical glass bottles
• Tamper/Child-Proof Cap + Orifice Reducer for integrity, sterility, and ease of use

Description

Semax is explored for its potential in cognitive enhancement, neuroprotection, and stroke rehabilitation.
Research suggests links to BDNF/NGF pathways, neuroplasticity, and modulation of stress and ischemic responses.

Benefits

• Attention and focus — studied for enhancing task performance and cognitive clarity
• Memory support — linked to improved recall and learning efficiency in research models
• Stress resilience — explored for modulating responses to acute and chronic stress
• Stroke recovery — clinical programs report increased BDNF and motor recovery benefits
• Neuroplasticity — associated with BDNF/TrkB and NGF signaling pathways

Localized Effects with Nasal Spray

• Rapid uptake through the nasal mucosa
• Direct access to central nervous system pathways linked to cognition and stress modulation
• Formulated with a specialized isotonic nasal vehicle to minimize irritation and dryness

What Researchers Use It For

• Mechanistic link to neurotrophins (BDNF/NGF) and plasticity pathways
• Transcriptomic responses in ischemic cortex models
• Clinical trials in Russia exploring cognition, attention, and stroke recovery
• Anti-aggregation properties studied in Aβ–metal interaction models

Identity & Specs

• Sequence: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
• Formula / M.W.: C37H51N9O10S, ~813.9 g/mol
• CAS: 80714-61-0
• Form: Sterile nasal spray solution
• Net per vial: 10 mL (~100 sprays)
• Total Content: 10 mg Semax per vial
• Purity: ≥99% (HPLC)
• Identity: MS-verified (per COA)
• Storage: Refrigerate 2–8 °C, protect from light

Selected Research

• PubChem entry — chemical identity:
  
  https://pubchem.ncbi.nlm.nih.gov/compound/Semax
  
• Ischemic stroke rehab study (2018) — BDNF increase & motor recovery:
  
  https://pubmed.ncbi.nlm.nih.gov/29798983/
  
• Genome-wide transcriptomic responses (2014):
  
  https://pmc.ncbi.nlm.nih.gov/articles/PMC3987924/
  
• Neurotrophin signaling (2006):
  
  https://pubmed.ncbi.nlm.nih.gov/16996037/
  
• NGF/BDNF dynamics (2009):
  
  https://pubmed.ncbi.nlm.nih.gov/19662538/
  
• Aβ–metal interaction study (ACS Chem Neurosci, 2021):
  
  https://pubs.acs.org/doi/10.1021/acschemneuro.1c00707
  

⚠️ Disclaimer

• This product is intended for laboratory research use only.

• Not for human or veterinary use.

• Not approved for diagnostic, therapeutic, or medical applications.

• Handle using appropriate laboratory safety procedures and personal protective equipment.